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rat anti mertk alexafluor700  (R&D Systems)


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    R&D Systems rat anti mertk alexafluor700
    Rat Anti Mertk Alexafluor700, supplied by R&D Systems, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rat+anti+mouse+mertk/pmc11390485-461-70-72?v=R%26D+Systems
    Average 92 stars, based on 1 article reviews
    rat anti mertk alexafluor700 - by Bioz Stars, 2026-08
    92/100 stars

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    Liver kinase B1 (LKB1) deficiency leads to a reduced number of alveolar macrophages (AMs) in the lung. A, Macrophage (CD45 + , MerTK + , and CD64 + ) populations in lung suspensions of LysM-cre × Stk11 fl/fl and littermate control ( Stk11 fl/fl ) mice: “classic” AMs (cAMs) (SiglecF high and CD11b neg ), “nonclassic” AMs (ncAMs) (SiglecF low and CD11b pos ), and interstitial macrophages (IMs) (SiglecF neg and CD11b high ). B–D, Numbers of cAMs, ncAMs, and IMs ( B ), percentage of dead cells ( C ), and percentage Ki-67–positive cells ( D ) in lung suspensions of LysM-cre × Stk11 fl/fl mice and littermate controls ( Stk11 fl/fl ). Data are shown as bar graphs representing mean with standard error of the mean for 5 mice per group. LysM-cre × Stk11 fl/fl mice were compared with littermate control ( Stk11 fl/fl ) mice using Student t tests. * P < .05; † P < .01; ‡ P < .001.

    Journal: The Journal of Infectious Diseases

    Article Title: Association of Myeloid Liver Kinase B1 Depletion With a Reduction in Alveolar Macrophage Numbers and an Impaired Host Defense During Gram-Negative Pneumonia

    doi: 10.1093/infdis/jiaa416

    Figure Lengend Snippet: Liver kinase B1 (LKB1) deficiency leads to a reduced number of alveolar macrophages (AMs) in the lung. A, Macrophage (CD45 + , MerTK + , and CD64 + ) populations in lung suspensions of LysM-cre × Stk11 fl/fl and littermate control ( Stk11 fl/fl ) mice: “classic” AMs (cAMs) (SiglecF high and CD11b neg ), “nonclassic” AMs (ncAMs) (SiglecF low and CD11b pos ), and interstitial macrophages (IMs) (SiglecF neg and CD11b high ). B–D, Numbers of cAMs, ncAMs, and IMs ( B ), percentage of dead cells ( C ), and percentage Ki-67–positive cells ( D ) in lung suspensions of LysM-cre × Stk11 fl/fl mice and littermate controls ( Stk11 fl/fl ). Data are shown as bar graphs representing mean with standard error of the mean for 5 mice per group. LysM-cre × Stk11 fl/fl mice were compared with littermate control ( Stk11 fl/fl ) mice using Student t tests. * P < .05; † P < .01; ‡ P < .001.

    Article Snippet: Cell subsets were identified by staining with fixable viability dye eFluor 780 (Invitrogen) and the following antibodies: rat anti-mouse CD16/CD32 (clone 93), rat anti-mouse CD45 phycoerythrin (PE)–eFluor610 or fluorescein isothiocyanate (FITC) (clone 30-F11), hamster anti-mouse CD11c peridinin-chlorophyll protein (PerCP)–cyanine 5,5 (Cy5,5) (clone HL3), rat anti-mouse CD11b PE–cyanine 7 (clone M1/70), rat anti-mouse Siglec-F Alexa Fluor 647 (clone E50-2440), rat anti-mouse Ly-6G Alexa Fluor 700 or allophycocyanin (clone 1A8), rat anti-mouse major histocompatibility complex class II Alexa Fluor 700 (clone M5/114.15.2), and rat anti-mouse CD24 allophycocyanin (clone M1/69) (all from BD Biosciences); mouse anti-mouse CD64 PerCP-Cy5,5 (clone X54-5/7.1), rat anti-mouse MerTK PE (clone 2B10C42), rat anti-mouse Ly-6G FITC (clone 1A8), and hamster anti-mouse CD103 PerCP-Cy5,5 (clone 2E7) (all from Biolegend); and rat anti-mouse Ly6C FITC (clone 1G7.G10; Miltenyi Biotec).

    Techniques: Control